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HaemaLogiX strengthens Board with appointment of Dr. Geoff Nichol

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7 July 2022

• Dr. Geoff Nichol, M.B., Ch.B., M.B.A., joins HaemaLogiX’s Board of Directors as Non-Executive Director, bringing nearly 30 years of global drug development experience

• Past achievements include approval of Augmentin BID for adults and children, plus foundational clinical development of breakthrough cancer immunotherapy checkpoint inhibitors, Yervoy and Optivo

HaemaLogiX Ltd, a clinical stage immuno-oncology biotech developing novel immunotherapies for patients with blood cancers, is pleased to announce the appointment of Dr. Geoff Nichol to its Board as Non-Executive Director.

Bryce Carmine, HaemaLogiX’s Chairman and CEO commented: “Geoff’s impressive, globally recognised background in drug development, and in particular, in antibody development, makes him a valuable contribution to the HaemaLogiX board. Importantly, during his time at Medarex, Geoff oversaw the preclinical and clinical development of KappaMab, our multiple myeloma drug candidate. He brings outstanding industry knowledge and a highly translatable skillset to our Board mix.

“We are delighted to welcome Geoff and look forward to his contributions as we continue to advance our immunotherapeutic pipeline.”

Dr. Nichol brings nearly 30 years’ experience in drug development. His first drug development success was at SmithKline Beecham with the approval of Augmentin BID in 1996 for adults and children for all indications.

As a VP at Novartis (1996-2002), he managed, successively, a clinical development therapeutic area, US Medical Affairs, and Global Project and Portfolio Management, with significant involvement in the Foradil and Xolair programs.

Dr. Nichol was SVP of Development at Medarex Inc, where he was responsible for the foundational clinical development of the breakthrough cancer immunotherapy checkpoint inhibitors Yervoy (Phase 1 through Phase 3) and Opdivo (Phase 1). Medarex was acquired by Bristol Myers Squibb (BMS) in 2009 and gained regulatory approval and commercial release of both these drugs. In recognition of the significance of these breakthrough therapies in 2018 the medical scientists who discovered these checkpoint drugs – Prof James Allison and Prof Tasuku Honjo - were awarded the Nobel Prize for Physiology or Medicine.

From 2011-2016 Dr. Nichol was EVP R&D at Sangamo BioSciences, a genome editing and gene therapy company. He managed the pre-clinical development of several IND candidates both in vivo and ex vivo in T cells and stem cells, and a gene therapy for haemophilia, all now in late-stage clinical trials.

In 2016, Dr. Nichol became Chief Medical Officer at BioMarin Pharmaceutical Inc, managing an active portfolio of clinical development programs, including the development and approval of Brineura for Batten disease, Palynziq for Phenylketonuria a VOXZOGO for achondroplasia, and phase 3 development of BMN 270, a leading investigational gene therapy for haemophilia. In 2021, Dr. Nichol transitioned from CMO into a Senior Advisor role with BioMarin and remained active with the company until mid-2022.

Dr. Nichol graduated in medicine from the Otago University Medical School in New Zealand and completed clinical advanced training in Thoracic Medicine in Christchurch New Zealand, Adelaide SA and London UK. He has an MBA from Warwick University, UK. He is a Fellow of the Royal Australasian College of Physicians. He resides is in the Bay area of San Francisco, USA.

“I am delighted to be joining the Board to guide strategy around the further development of KappaMab as well as HaemaLogiX’s other pipeline assets,” said incoming Non-Executive Director, Dr. Nichol. “I look forward to working with the team to bring forward much needed new therapies for patients with multiple myeloma and other diseases.”

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